KMID : 0358419970400010123
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Korean Journal of Obstetrics and Gynecology 1997 Volume.40 No. 1 p.123 ~ p.128
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Comparison of Early and Mid-Second-Trimester Amniocentesis
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Abstract
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We sought to determine whether early amniocentesis is a safe and acceptable method of genetic evaluation in early pregnancy. During The 20-month period from February 1994 to September 1995, 80 consecutive early amniocentesis were performed
transabdominally at 12+3 -14+6 weeks of gestation and 305 consecutive mid-second-trimester transabdominal amniocenteses were performed at 16+0-18+0 weeks of gestation. All amniotic fluid samples were cultured using flask method. There were no
significant differences between the early and mid-second-trimester amniocenteses in failed sampling, ambiguous results, pregnancy loss within 4 weeks after the procedure, pregnancy loss from 4 weeks after procedure to 28 weeks of gestation,
preterm
birth, and perinatal death. We may conclude that early amniocentesis is a safe and acceptable method for prenatal diagnosis.
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KEYWORD
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